Role of Peoxisome Proliferator Activator Receptor on Blood Retinal Barrier Breakdown
نویسندگان
چکیده
منابع مشابه
Role of Peoxisome Proliferator Activator Receptor γ on Blood Retinal Barrier Breakdown
THE RETINAL VESSELS HAVE TWO BARRIERS: the retinal pigment epithelium and the retinal vascular endothelium. Each barrier exhibits increased permeability under various pathological conditions. This condition is referred to as blood retinal barrier (BRB) breakdown. Clinically, the most frequently encountered condition causing BRB breakdown is diabetic retinopathy. In recent studies, inflammation ...
متن کاملThe Role of Peroxisome Proliferator Activator Receptor Alpha in Cerebral Ischemia-Reperfusion Injury; a Review Study
Peroxisome proliferator-activated receptor alpha (PPAR-α), which belongs to the nuclear receptor family of ligand-activated transcription factors, was first described as gene regulators for metabolic pathways including lipid metabolism, insulin sensitivity, and glucose homeostasis. Were raised. This nuclear receptor is widely expressed in various tissues, providing a wide range of effects to st...
متن کاملStudies on the permeability of the blood-retinal barrier. 3. Breakdown of the blood-retinal barrier by circulatory disturbances.
AN alteration of vascular permeability has been proposed by numerous authors as the key factor underlying the development of most vascular retinopathies. Among others, Hanum (1939), Ballantyne (1945, 1946), Friedenwald (1950), and Ashton (1951, 1963) have stressed the probable importance of a change of vascular permeability in the formation of microaneurysms and development of diabetic retinopa...
متن کاملP45: The Role of Blood-Brain Barrier Breakdown Following Traumatic Brain in Post-Traumatic Epilepsy
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملEarly breakdown of the blood-retinal barrier in diabetes.
The blood-retinal barrier plays an important part in the processes of retinal pathophysiology. A new clinical method for the study of the blood-retinal barrier by vitreous fluorophotometry appears to satisfy the necessary requirements in that it is quantitative and shows good reproducibility and high sensitivity. The application of this method to a series of diabetic patients with apparently "...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PPAR Research
سال: 2008
ISSN: 1687-4757,1687-4765
DOI: 10.1155/2008/679237